Background: Metabolic syndrome is associated with occurrence of cardiovascular disease and type 2 DM. Insulin resistance commonly accompanies metabolic syndrome and causes not only elevation of blood pressure and blood sugar but also dyslipidemia. Excessive sodium intake is known to play a role in causing insulin resistance and high blood glucose. The purpose of this study was to elucidate the relationship between urine sodium and fasting blood glucose in participants with metabolic syndrome.

Methods: This study included 1,646 participants with metabolic syndrome who underwent a medical check-up in the Korea National Health and Nutrition Examination Surveys in 2011. Urine sodium data were divided into 3 groups according to tertile. We analysed the relationship between urine sodium and fasting blood glucose.

Results: This study found that there is a significant relationship between participants’ general characteristics and urine sodium. In detail, those independent variables are age, BMI, waist circumference, blood pressure, fasting blood glucose, energy intake, and sodium intake. It is shown that urine sodium has a statistically significant negative relationship with FBG (fasting blood glucose), as shown from ANCOVA after adjusting for age, gender, BMI, smoking, alcohol and hypertension.(p=0.001)

Conclusion: Urine sodium and fasting blood glucose in patients with metabolic syndrome were significantly and negatively correlated with each other.