Korean J Fam Pract. 2017; 7(4): 470-476  https://doi.org/10.21215/kjfp.2017.7.4.470
Associaiton between Metabolic Syndrome and Microalbuminuria: Data Analysis from the 6th Korea National Health and Nutrition Examination Survey
Min Yong Choi1, Bora Yoo1, Du-na Hwang1, Young-min Park2,*
1Department of Family Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul; 2Department of Family Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea
Young-min Park
Tel: +82-31-900-0740, Fax: +82-31-900-0049
E-mail: steelmess@naver.com
Received: June 30, 2016; Revised: October 9, 2016; Accepted: October 11, 2016; Published online: August 20, 2017.
© Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Metabolic syndrome (MetS) and microalbuminuria are well-known risk factors for chronic kidney disease and cardiovascular disease. Previous studies suggest that albumin-creatinine ratio and glomerular filtration rate are related to MetS. This study aimed to evaluate the associations between metabolic characteristics and microalbuminuria as a predictor of poor renal outcomes.
Methods: This study used the data collected from the Sixth Korea National Health and Nutrition Examination Survey. The total number of participants older than 20 years was 6,793. MetS was defined according to the recommendation from American Heart Association/National Heart Lung and Blood Institute. The crude and multivariate-adjusted odds ratios (OR) of microalbuminuria were calculated using logistic regression models with each component of MetS.
Results: Microalbuminuria was observed in 267 (13.4%) of the 1,920 subjects with MetS, and in 221 (4.2%) of the 4,873 subjects without MetS. The multivariate-adjusted OR of microalbuminuria in participants with MetS was 2.49 (95% confidence interval [CI], 1.93 to 3.21). The multivariateadjusted ORs of microalbuminuria in the participants with abdominal obesity, hypertriglyceridemia, high blood pressure, and impaired fasting glucose were 1.30 (95% CI, 1.01 to 1.67), 1.46 (95% CI, 1.13 to 1.87), 2.14 (95% CI, 1.67 to 2.75), and 1.85 (95% CI, 1.45 to 2.36), respectively (P<0.05).
Conclusion: These findings from a large population-based cross-sectional study of Korean adults suggest that MetS and microalbuminuria, based on the spot urine test, are associated.
Keywords: Microalbuminuria; Metabolic Syndrome; Hypertension; Dyslipidemia; Obesity
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