Korean J Fam Pract. 2017; 7(4): 497-502  https://doi.org/10.21215/kjfp.2017.7.4.497
The Association between Weight Change and Depression in Korean Adults: The Korea National Health and Nutrition Examination Survey 2010-2012
Hye-Rim Jeon1, Ji Eun Lee1, Soo Lee1, Kyung-Do Han2, Suk Won Park1, Ji Hyun Kim1, Jin Hee Yoon1, Kyung-Hwan Cho1, Yang-Hyun Kim1,*
1Department of Family Medicine, Korea University College of Medicine; 2Department of Medical Statistics, College of Medicine, The Catholic University of Korea, Seoul, Korea
Yang-Hyun Kim
Tel: +82-2-871-1160, Fax: +82-2-928-8083
E-mail: mrchir@naver.com
Received: July 8, 2016; Revised: September 13, 2016; Accepted: September 17, 2016; Published online: August 20, 2017.
© Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Obesity is one of the public health problems in South Korea. It has been known that various physical and psychological diseases, such as depression, are associated with obesity. Some studies have found that subjects with obesity, who had higher rates of depression, exhibited more weight change. Therefore, we evaluated relationship between weight change and depression in a representative sample of the Korean population.
Methods: We analyzed the data of 17,813 participants (7,550 men and 10,263 women) from the 2010 to 2012 Korea National Health Survey. Depression was estimated based on cases of depression that had been diagnosed by a physician. Multivariate logistic regression analyses were performed to examine the relationship between weight change and depression.
Results: The weight gained during the past 1 year increased the risk of depression (odds ratio [OR]=1.566, 95% confidence interval [Cl]=1.218–2.013, P=0.002). This association was statistically significant among women (OR=1.603, 95% CI=1.210–2.122). Compared to the obesity group (body mass index ≥25), the non-obesity group had a higher adjusted OR for depression (OR=1.670, 95% CI=1.195–2.334). Those aged 40 to 60 years (OR=1.797, 95% CI=1.284–2.515) and over 60 years (OR=1.889, 95% CI=1.003–3.557) had higher ORs for depression, while those aged under 40 years showed no significant differences.
Conclusion: Weight gain in the past 1 year is associated with depression, especially in subjects who are female, non-obese, and aged over 40 years. Further research using a prospective design is needed to investigate the interaction between weight change and depression.
Keywords: Weight Change; Depression; Obesity; Korea National Health And Nutrition Examination Survey V
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