Korean J Fam Pract. 2017; 7(6): 870-876  https://doi.org/10.21215/kjfp.2017.7.6.870
Association between Sarcopenia and Health-Related Quality of Life in Korean Adults: Based on the Fifth Korean National Health and Nutrition Examination Survey (2010-2011)
Jeong Min Oh, Ji-Ho Choi*, Yeon Ji Lee, Yu Rim Lee, Nam Hee Youn, Hyeun Jin Song
Department of Family Medicine, Inha University College of Medicine, Incheon, Korea
Ji-Ho Choi
Tel: +82-32-890-3547, Fax: +82-32-890-2195
E-mail: wisdom@inha.ac.kr
Received: March 8, 2017; Revised: July 30, 2017; Accepted: August 7, 2017; Published online: December 20, 2017.
© Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Sarcopenia is defined as a loss of muscle mass leading to decreased muscle strength, physical activity, and increased mortality. Health-related quality of life (HRQoL) has been identified as a factor in various medical outcomes including death, and has become an important consideration in health care. We aimed to analyze the association between sarcopenia and HRQoL in Korean adults older than 19 years.
Methods: We included 2,300 men and 2,849 women who participated in the Korea National Health and Nutrition Examination Survey from 2010 to 2011. Sarcopenia was defined as appendicular skeletal muscle mass divided by weight (%) below 2 standard deviations of the sex-specific mean for young adults. The cutoff point for sarcopenia was 29.1% in men and 23.0% in women. HRQoL was measured with the Euro quality of life-5 dimension (EQ-5D) instrument. Logistic regression analysis was performed to evaluate the relationship between sarcopenia and HRQoL.
Results: The prevalence of sarcopenia was 14.5% in men and 19.7% in women. The EQ-5D index score was significantly lower and the rate of difficulty with individual components of HRQoL was higher in the sarcopenic group. After adjustment for age, body mass index, lumbar spine BMD, chronic disease, smoking, alcohol, regular exercise, and education, the odds ratios for problems with mobility were 1.62 in men and 1.31 in women; however, the difference was not statistically significant for women.
Conclusion: Sarcopenia was associated with poor quality of life, especially with regard to mobility and depression/anxiety. Greater consideration of sarcopenia is needed at a younger age to prevent and manage poor quality of life at an older age.
Keywords: Sarcopenia; Euro Quality of Life-5 Dimension; Health-Related Quality of Life
References
  1. Hong S, Choi WH. Clinical and physiopathological mechanism of sarcopenia. Korean J Med 2012; 83: 444-54.
    CrossRef
  2. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, et al. Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in older people. Age Ageing 2010;39: 412-23.
    Pubmed KoreaMed CrossRef
  3. Morley JE. Diabetes, sarcopenia, and frailty. Clin Geriatr Med 2008; 24: 45569, vi.
    Pubmed CrossRef
  4. Kim TN, Park MS, Yang SJ, Yoo HJ, Kang HJ, Song W, et al. Prevalence and determinant factors of sarcopenia in patients with type 2 diabetes: the Korean Sarcopenic Obesity Study (KSOS). Diabetes Care 2010; 33: 1497-9.
    Pubmed KoreaMed CrossRef
  5. Testa MA, Simonson DC. Assessment of quality-of-life outcomes. N Engl J Med 1996; 334: 835-40.
    Pubmed CrossRef
  6. Otero-Rodríguez A, León-Muñoz LM, Balboa-Castillo T, Banegas JR, RodríguezArtalejo F, Guallar-Castillón P. Change in health-related quality of life as a predictor of mortality in the older adults. Qual Life Res 2010; 19: 1523.
    Pubmed CrossRef
  7. Rodríguez-Artalejo F, Guallar-Castillón P, Pascual CR, Otero CM, Montes AO, García AN, et al. Health-related quality of life as a predictor of hospital readmission and death among patients with heart failure. Arch Intern Med 2005; 165: 1274-9.
    Pubmed CrossRef
  8. Lee SK, Lee JA, Kim JY, Kim YZ, Park HS. The risk factors of sarcopenia among Korean elderly men: based on 2009 Korean national health and nutritional examination survey data. Korean J Obes 2014; 23: 23-31.
    CrossRef
  9. Kim YS, Lee Y, Chung YS, Lee DJ, Joo NS, Hong D, et al. Prevalence of sarcopenia and sarcopenic obesity in the Korean population based on the Fourth Korean National Health and Nutritional Examination Surveys. J Gerontol A Biol Sci Med Sci 2012; 67: 1107-13.
    Pubmed CrossRef
  10. Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQol Group. Ann Med 2001; 33: 337-43.
    Pubmed CrossRef
  11. Korean Centers for Disease Control and Prevention. The report of quality weighted health related quality of life. Seoul: Korean Centers for Disease Control and Prevention; 2007.
  12. Lee YH, Choi JS, Rhee JA, Ryu SY, Shin MH, Kim JH. A study on the application of the Korean valuation weights for EuroQoL-5 dimension. Korean J Health Educ Promot 2009; 26: 1-13.
  13. Kim JS, Oh MK, Park BK, Lee MK, Kim GJ. Screening criteria of alcoholismby alcohol use disorders identification test (AUDIT) in Korea. J Korean Acad Fam Med 1999; 20: 1152-9.
  14. Rosenberg IH. Sarcopenia: origins and clinical relevance. J Nutr 1997; 127(5 Suppl): 990S-991S.
    Pubmed
  15. Baumgartner RN, Koehler KM, Gallagher D, Romero L, Heymsfield SB, Ross RR, et al. Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol 1998; 147: 755-63.
    Pubmed CrossRef
  16. Kwon HJ, Ha YC, Park HM. Prevalence of sarcopenia in the Korean woman based on the Korean National Health and Nutritional Examination Surveys. J Bone Metab 2016; 23: 23-6.
    Pubmed KoreaMed CrossRef
  17. Janssen I, Heymsfield SB, Ross R. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc 2002; 50: 889-96.
    Pubmed CrossRef
  18. Meng NH, Li CI, Liu CS, Lin WY, Lin CH, Chang CK, et al. Sarcopenia defined by combining height- and weight-adjusted skeletal muscle indices is closely associated with poor physical performance. J Aging Phys Act 2015;23: 597-606.
    Pubmed CrossRef
  19. Kim KM, Jang HC, Lim S. Differences among skeletal muscle mass indices derived from height-, weight-, and body mass index-adjusted models in assessing sarcopenia. Korean J Intern Med 2016; 31: 643-50.
    Pubmed KoreaMed CrossRef
  20. Go SW, Cha YH, Lee JA, Park HS. Association between sarcopenia, bone density, and health-related quality of life in Korean men. Korean J Fam Med 2013; 34: 281-8.
    Pubmed KoreaMed CrossRef
  21. Liu LK, Lee WJ, Liu CL, Chen LY, Lin MH, Peng LN, et al. Age-related skeletal muscle mass loss and physical performance in Taiwan: implications to diagnostic strategy of sarcopenia in Asia. Geriatr Gerontol Int 2013; 13: 96471.
    Pubmed CrossRef
  22. Delmonico MJ, Harris TB, Lee JS, Visser M, Nevitt M, Kritchevsky SB, et al. Alternative definitions of sarcopenia, lower extremity performance, and functional impairment with aging in older men and women. J Am Geriatr Soc 2007; 55: 769-74.
    Pubmed CrossRef


This Article

e-submission

Archives