Korean J Fam Pract. 2017; 7(6): 915-921  https://doi.org/10.21215/kjfp.2017.7.6.915
Effects of Pneumococcal and Influenza Vaccine in Elderly Inpatients
Seong Hi Cheon, Hye In Kim, Keun Mi Lee, Seung Pil Jung*
Department of Family Medicine, Yeungnam University College of Medicine, Daegu, Korea
Seung Pil Jung
Tel: +82-53-620-3540, Fax: +82-53-654-2413
E-mail: spjung@ynu.ac.kr
Received: May 31, 2017; Accepted: July 5, 2017; Published online: December 20, 2017.
© Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Pneumococcal and influenza vaccination are effective in reducing morbidity and mortality. Our study investigated the effects of pneumococcal and influenza vaccination in elderly inpatients.
Methods: The medical records of 1,076 inpatients over 65 years old in the Department of Internal Medicine in Yeungnam University Medical Center (Deagu, Korea) between October 2015 and March 2016 were reviewed. Vaccination data were obtained from the Korea Centers for Disease Control and Prevention web system. The chi-square test was used to analyze univariate factors associated with pneumonia and mortality. To estimate probabilities of binary responses with vaccines as predictor variables, we performed logistic regressions for multivariate analyses after adjusting for confounding factors. The analyses were performed using IBM SPSS Statistics ver. 23.0. A P-value<0.05 was considered to indicate a significant difference between groups.
Results: Pneumococcal and influenza vaccination coverage rate were 73.4% and 77.2% respectively. There were statistical associations between pneumococcal conjugate vaccine and pneumonia in the group aged 75 years and over and pneumococcal conjugate vaccine and mortality in the total group. Influenza vaccination and mortality associated in the total group and the group aged 65–75 years. Pneumonia-associated morbidity was high with pneumococcal conjugate vaccine in the group aged 75 years and over; influenza vaccination decreased the incidence of pneumonia in the total group.
Conclusion: In elderly inpatients, the pneumococcal vaccination rate was high, but its effectiveness was uncertain. However, influenza vaccination had a positive effect in reducing pneumonia-associated morbidity.
Keywords: Pneumococcal Vaccines; Influenza Vaccines; Pneumonia; Mortality; Elderly
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