Korean J Fam Pract. 2018; 8(2): 292-298  https://doi.org/10.21215/kjfp.2018.8.2.292
Associations between Osteoarthritis and Metabolic Syndrome in Korean Adult: The 5th Korean National Health and Nutrition Examination Survey, 2010-2012
Hyokyoung Cho, Yu-Lee Kim*, Yong-Jae Jeong, Jaehoon Jung
Department of Family Medicine, Busan Medical Center, Busan, Korea
Yu-Lee Kim
Tel: +82-51-507-3000, Fax: +82-51-507-3001
E-mail: 07721052@hanmail.net
ORCID: http://orcid.org/0000-0002-6371-2609
Received: April 3, 2017; Revised: August 1, 2017; Accepted: August 11, 2017; Published online: April 20, 2018.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: Osteoarthritis (OA) is the most common type of joint disease, and metabolic syndrome (MetS) is considered a major risk factor of OA. In the present study, the relationship between OA and MetS in Koreans was examined using data from the fifth Korean National Health and Nutrition Examination Survey (KNHANES).
Methods: The present study used data from the fifth KNHANES, conducted between 2010 and 2012. To investigate the association between the components of OA and MetS, we analyzed the mean values of 5 components of MetS, namely, waist circumference (WC), triglyceride level, high-density lipoprotein-cholesterol level, systolic blood pressure (SBP), and fasting blood glucose level. Multivariate logistic regression analysis was conducted to examine the association of OA with MetS and MetS parameters after adjusting for confounding factors .
Results: The prevalence rate of MetS in OA patients showed a gradual increasing trend in each age group except the ≥80 years age group. Among the MetS parameters, high SBP and WC were associated with an increased prevalence of OA in men and women before adjustment for covariates , but the significance of WC disappeared upon adjustment for age and confounding factors. A high WC among women in their 50s and a high SBP among men in their 60s were associated with an increased prevalence of OA . Conclusion: This study showed that WC in women and high SBP in men were associated with OA among Korean subjects.
Keywords: Osteoarthritis; Metabolic Syndrome; Waist Circumference; Hypertension; Korean National Health and Nutrition Examination Survey
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