Korean J Fam Pract. 2018; 8(4): 623-625  https://doi.org/10.21215/kjfp.2018.8.4.623
Risk Factors for Acute Exacerbation on Asthma in Adult Patient Admissioned at Hospital
Se-Jung Jang, Kyo-jin Seok*, Kwang-hyun Shin, Joon-beom Park
Department of Family Medicine, Kwak’s Hospital, Daegu, Korea
Kyo-jin Seok Tel: +82-53-605-3580, Fax: +82-53-605-3593 E-mail: sniper912@hanmail.net ORCID: http://orcid.org/0000-0002-1402-2011
Received: May 12, 2017; Revised: October 18, 2017; Accepted: October 19, 2017; Published online: August 20, 2018.
© The Korean Academy of Family Medicine. All rights reserved.

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Background: Asthma exacerbations are caused by various risk factors. Available information suggests that women are more frequently and more severely affected with asthma. Therefore, this study aimed to determine the risk factors for asthma exacerbations in female adult patients.
Methods: An unmatched case-control study involving 53 cases and 45 controls was conducted from January to December 2015. Female asthmatic patients with exacerbations admitted to the Kwak’s Hospital emergency unit were selected as cases. The controls were patients with asthma recruited from the outpatient department who had not experienced an exacerbation in the past. The study variables were age, age at diagnosis, initial forced expiratory volume in one second, upper respiratory tract infections, smoking, use of corticosteroids, hypertension, diabetes mellitus, cardiovascular disease, cerebrovascular accident, allergy, and hysterectomy. Bivariate statistical analysis was performed using the SPSS version 20 (IBM Co.) to identify the risk factors for exacerbations.
Results: No significant P-value was observed in hysterectomy and menopause; however, significant P-value was found in the upper respiratory infection in the bivariate linguistic analysis.
Conclusion: In female patients who experienced exacerbation, further research on the influence of sex hormones such as hysterectomy or menopausal status should be conducted in the future.
Keywords: Asthma Exacerbation; Adult Female Patients; Risk Factors; Hysterectomy; Menopause; Upper Respiratory Tract Infection
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