Korean J Fam Pract 2019; 9(3): 272-276  https://doi.org/10.21215/kjfp.2019.9.3.272
The Relationship between Serum Vitamin D Level and Muscle Strength in Koreans: Using Korean National Health and Nutrition Examination Survey
Sun Whan Kim, Ji Hoon Jung*, Dong Won Lee, Sang Hyun Cho, Hyun Woo Kim, Jung Hwan Yoon
Department of Family Medicine, Hanageneral Hospital, Cheongju, Korea
Ji Hoon Jung
Tel: +82-43-230-6230, Fax: +82-43-230-6231
E-mail: gurofm@naver.com
Received: August 8, 2018; Revised: January 3, 2019; Accepted: January 31, 2019; Published online: June 20, 2019.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Vitamin D is a hormone required by the human body. Several studies have shown that vitamin D helps improve muscle strength. The purpose of our study was to examine the relationship between vitamin D levels and muscle strength in Korean adults.
Methods: The Korea National Health and Nutrition Examination Survey was conducted in the Korean population from 2009 to 2011. We surveyed 859 men and 944 women aged between 20 and 65 years. We investigated age, blood pressure, exercise frequency, heart rate, height, body weight, waist circumference, body mass index, serum vitamin D level, and hand grip strength. We analyzed the relationship between serum vitamin D level and hand grip strength using the linear regression test.
Results: On statistical analysis, vitamin D levels showed a significantly positive correlation with only grip strength. However, after adjusting for all other variables, no positive correlation was observed between vitamin D levels and grip strength.
Conclusion: No significant correlation was observed between vitamin D levels and grip strength. Further research is needed on this topic.
Keywords: Vitamin D; Muscle Strength; Hand Strength; Exercise
References
  1. Ziambaras K, Dagogo-Jack S. Reversible muscle weakness in patients with vitamin D deficiency. West J Med 1997; 167: 435-9.
    Pubmed KoreaMed
  2. Choi HJ. New insight into the action of vitamin D. Korean J Fam Med 2011;32: 89-96.
    CrossRef
  3. Bouillon R, Bischoff-Ferrari H, Willett W. Vitamin D and health: perspectives from mice and man. J Bone Miner Res 2008; 23: 974-9.
    Pubmed CrossRef
  4. Gunton JE, Girgis CM. Vitamin D and muscle. Bone Rep 2018; 8: 163-7.
    Pubmed KoreaMed CrossRef
  5. Lips P. Vitamin D deficiency and secondary hyperparathyroidism in the elderly:consequences for bone loss and fractures and therapeutic implications. Endocr Rev 2001; 22: 477-501.
    Pubmed CrossRef
  6. Wolff AE, Jones AN, Hansen KE. Vitamin D and musculoskeletal health. Nat Clin Pract Rheumatol 2008; 4: 580-8.
    Pubmed CrossRef
  7. Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB, Orav JE, Stuck AE, Theiler R, et al. Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. BMJ 2009; 339:b3692.
    Pubmed KoreaMed CrossRef
  8. Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC, Staehelin HB, Bazemore MG, Zee RY, et al. Effect of vitamin D on falls: a meta-analysis. JAMA 2004; 291: 1999-2006.
    Pubmed CrossRef
  9. Rejnmark L. Effects of vitamin d on muscle function and performance: a review of evidence from randomized controlled trials. Ther Adv Chronic Dis 2011; 2: 25-37.
    Pubmed KoreaMed CrossRef
  10. Park HA, Kim SY. Recent advance on vitamin D. J Korean Med Assoc 2013;56: 310-8.
    CrossRef
  11. Stockton KA, Mengersen K, Paratz JD, Kandiah D, Bennell KL. Effect of vitamin D supplementation on muscle strength: a systematic review and meta-analysis. Osteoporos Int 2011; 22: 859-71.
    Pubmed CrossRef
  12. Moreira-Pfrimer LD, Pedrosa MA, Teixeira L, Lazaretti-Castro M. Treatment of vitamin D deficiency increases lower limb muscle strength in institutionalized older people independently of regular physical activity: a randomized double-blind controlled trial. Ann Nutr Metab 2009; 54: 291-300.
    Pubmed CrossRef
  13. Flicker L, MacInnis RJ, Stein MS, Scherer SC, Mead KE, Nowson CA, et al. Should older people in residential care receive vitamin D to prevent falls? Results of a randomized trial. J Am Geriatr Soc 2005; 53: 1881-8.
    Pubmed CrossRef
  14. Bischoff HA, Stähelin HB, Dick W, Akos R, Knecht M, Salis C, et al. Effects of vitamin D and calcium supplementation on falls: a randomized controlled trial. J Bone Miner Res 2003; 18: 343-51.
    Pubmed CrossRef
  15. Jones G, Strugnell SA, DeLuca HF. Current understanding of the molecular actions of vitamin D. Physiol Rev 1998; 78: 1193-231.
    Pubmed CrossRef
  16. Cherniack EP, Florez HJ, Troen BR. Emerging therapies to treat frailty syndrome in the elderly. Altern Med Rev 2007; 12: 246-58.
    Pubmed
  17. Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-Hughes B. Fracture prevention with vitamin D supplementation: a metaanalysis of randomized controlled trials. JAMA 2005; 293: 2257-64.
    Pubmed CrossRef

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