Korean J Fam Pract. 2017; 7(2): 233-238  https://doi.org/10.21215/kjfp.2017.7.2.233
Clinical Characteristics of Exercise-Induced Rhabdomyolysis: Difference according to Creatinine
SohYeon Ahn, JuHyun Lee*, SoShin Kye, NaRa Lee, MinWoong Lee, JaYoung Kim, MinShik Shin
Department of Family Medicine, National Police Hospital, Seoul, Korea
JuHyun Lee
Tel: +82-2-3400-1395, Fax: +82-2-3400-1291
E-mail: happyola@naver.com
Received: March 16, 2016; Revised: August 25, 2016; Accepted: September 1, 2016; Published online: April 20, 2017.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Exercise-induced rhabdomyolysis occurs in special situations, such as strenuous exercise or training of troops, and early diagnosis is difficult without suspicion. We investigated the clinical characteristics of exercise-induced rhabdomyolysis, and tried to identify factors associated with acute kidney injury, that often occurs as a complication.
Methods: One hundred and forty-two rhabdomyolysis cases were selected by reviewing hospital records of Combat and Auxiliary Police patients who were hospitalized at the National Police Hospital from 2007 to 2015. The records were analyzed based on the laboratory findings and clinical manifestations. The factors contributing to acute kidney injury were confirmed by comparing two groups: one with an elevated serum creatinine levels and one with a serum creatinine within the normal limits.
Results: The elevated serum creatinine group had a significantly higher uric acid and phosphate level and a lower albumin and sodium than the group with a normal serum creatinine. Logistic regression analysis revealed that high blood phosphate levels and low urine acidity are associated with a higher creatinine level.
Conclusion: The increase in serum creatine phosphokinase cannot predict the severity of the disease and the risk of complications. General body aches or pain in the trunk associated with a full body workout is thought to increase the likelihood of progression to acute kidney injury. There needs to be more careful observation in cases of high blood phosphate level and low urine acidity.
Keywords: Exercise-Induced; Rhabdomyolysis; Acute Kidney Injury; Creatinine
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