Korean J Fam Pract. 2017; 7(6): 818-823  https://doi.org/10.21215/kjfp.2017.7.6.818
The Correlationship between the Ratio of Triglyceride to High-Density Lipoprotein Cholesterol and Non-Alcoholic Fatty Liver Disease
Han Na Seo1, Hye Mi Lee1, Tai Chi Lin1, Joon Suk Oh1, Hye Rim Kong2, Sung A Cho2, Bong Gyu Choi1,*
1Department of Family Medicine, Gwangmyeong Sungae Hospital, Gwangmyeong; 2Department of Family Medicine, Sungae Hospital, Seoul, Korea
Bong Gyu Choi
Tel: +82-2-2680-7114, Fax: +82-2-2680-7755
E-mail: stapy74@hanmail.net
Received: March 3, 2017; Revised: April 30, 2017; Accepted: May 26, 2017; Published online: December 20, 2017.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: This study aimed to elucidate the relationship between the ratio of triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C) and non-alcoholic fatty liver disease (NAFLD).
Methods: A total of 724 subjects were screened at the health center of a Gwangmyeong Sungae Hospital in 2015. Of those screened, 389 were selected after excluding subjects with significant alcohol consumption, evidence of viral or toxic hepatitis, significant liver or renal dysfunction, or other disease. All subjects underwent anthropometric measurement, laboratory examination, and abdominal ultrasonography. We compared the ratio of TG to HDL-C between the NAFLD group and the control group to identify a correlation. The ratio of TG to HDL-C was divided into quartiles and the prevalence of NAFLD was determined.
Results: The prevalence of NAFLD was 45.2%. The prevalence of hypertriglyceridemia, low HDL-C, hyperglycemia, and obesity was higher in the NAFLD group than in the control group. In addition, the ratio of TG to HDL-C was higher in the NAFLD group than in the control group. As the ratio of TG to HDL-C increased, the odds ratio and 95% confidence interval for the prevalence of NAFLD showed a tendency toward a significant increase in both in adjusted and unadjusted models.
Conclusion: The ratio of TG to HDL-C was closely correlated with NAFLD.
Keywords: High Density Lipoprotein Cholesterol; Dyslipidemia; Non-Alcoholic Fatty Liver Disease; Ultrasonography
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