Korean J Fam Pract. 2017; 7(6): 870-876  https://doi.org/10.21215/kjfp.2017.7.6.870
Association between Sarcopenia and Health-Related Quality of Life in Korean Adults: Based on the Fifth Korean National Health and Nutrition Examination Survey (2010-2011)
Jeong Min Oh, Ji-Ho Choi*, Yeon Ji Lee, Yu Rim Lee, Nam Hee Youn, Hyeun Jin Song
Department of Family Medicine, Inha University College of Medicine, Incheon, Korea
Ji-Ho Choi
Tel: +82-32-890-3547, Fax: +82-32-890-2195
E-mail: wisdom@inha.ac.kr
Received: March 8, 2017; Revised: July 30, 2017; Accepted: August 7, 2017; Published online: December 20, 2017.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Sarcopenia is defined as a loss of muscle mass leading to decreased muscle strength, physical activity, and increased mortality. Health-related quality of life (HRQoL) has been identified as a factor in various medical outcomes including death, and has become an important consideration in health care. We aimed to analyze the association between sarcopenia and HRQoL in Korean adults older than 19 years.
Methods: We included 2,300 men and 2,849 women who participated in the Korea National Health and Nutrition Examination Survey from 2010 to 2011. Sarcopenia was defined as appendicular skeletal muscle mass divided by weight (%) below 2 standard deviations of the sex-specific mean for young adults. The cutoff point for sarcopenia was 29.1% in men and 23.0% in women. HRQoL was measured with the Euro quality of life-5 dimension (EQ-5D) instrument. Logistic regression analysis was performed to evaluate the relationship between sarcopenia and HRQoL.
Results: The prevalence of sarcopenia was 14.5% in men and 19.7% in women. The EQ-5D index score was significantly lower and the rate of difficulty with individual components of HRQoL was higher in the sarcopenic group. After adjustment for age, body mass index, lumbar spine BMD, chronic disease, smoking, alcohol, regular exercise, and education, the odds ratios for problems with mobility were 1.62 in men and 1.31 in women; however, the difference was not statistically significant for women.
Conclusion: Sarcopenia was associated with poor quality of life, especially with regard to mobility and depression/anxiety. Greater consideration of sarcopenia is needed at a younger age to prevent and manage poor quality of life at an older age.
Keywords: Sarcopenia; Euro Quality of Life-5 Dimension; Health-Related Quality of Life
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