Korean J Fam Pract. 2017; 7(6): 909-914  https://doi.org/10.21215/kjfp.2017.7.6.909
The Relationship between Triglyceride, Triglyceride to High Density Lipoprotein Cholesterol Ratio and Brachial Ankle Pulse Wave Velocity among Healthy Adults
Jae Hyun Youn, Ji Hoon Jung, Jung Hyun Kim*, Hyun Woo Kim, Byung Shik Cho, Sun Whan Kim, Seung Jin Jung, Dong Won Lee, Sang Hyun Cho
Department of Family Medicine, Hana General Hospital, Cheongju, Korea
Jung Hyun Kim
Tel: +82-43-230-6555, Fax: +82-43-235-5300
E-mail: astrobass@hanmail.net
Received: May 15, 2017; Revised: August 7, 2017; Accepted: August 15, 2017; Published online: December 20, 2017.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: This study investigated the correlation between triglyceride (TG) or the triglyceride to high density lipoprotein cholesterol (TG/HDL-C) ratio and the brachial ankle pulse wave velocity (baPWV), which is widely used as an indirect measure of atherosclerosis.
Methods: The study included 1,331 adults (721 men, 610 women) aged between 20 and 65 years with no underlying disease, who underwent baPWV measurement at a general health checkup between May and October 2015. Multiple linear stepwise regression analysis was performed for TG and the TG/HDL-C ratio, using the results of univariate correlation analysis between baPWV and body measurements and biochemical parameters as variables, in addition to age, alcohol use, and smoking history.
Results: There was a significant difference in baPWV according to sex (male>female), and a positive correlation was found between baPWV and TG or the TG/HDL-C ratio in univariate analysis. Regression analysis of TG or the TG/HDL-C ratio and baPWV, after correction by calibrating all variables, showed β=0.078 and P=0.046 for TG and β=0.1 and P=0.004 for the TG/HDL-C ratio for men. For women, β=0.124 and P<0.001 for TG and β=0.112 and P=0.001 for the TG/HDL-C ratio. The results showed a significant relationship in both men and women.
Conclusion: There was a significant relationship between TG or the TG/HDL-C ratio and baPWV after controlling for demographic factors in adults without underlying disease.
Keywords: Arterial Stiffness; Brachial Ankle Pulse Wave Velocity; Triglyceride; Triglyceride to High Density Lipoprotein Cholesterol Ratio
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