Korean J Fam Pract. 2018; 8(4): 535-541  https://doi.org/10.21215/kjfp.2018.8.4.535
Association between Sleep Duration and Osteoarthritis in Korean Adults Over 30 Years Old: The Sixth Korea National Health and Nutrition Examination Survey (2013-2015)
Jong Il Kim, Hee Joo Lee, Hyun Jin Kim, Rae Ho Chung*
Department of Family Medicine, Daegu Veterans Hospital, Daegu, Korea
Rae Ho Chung Tel: +82-53-630-7000, Fax: +82-53-630-7849 E-mail: urierl@daum.net ORCID: http://orcid.org/0000-0001-7629-9449
Received: June 30, 2017; Revised: November 2, 2017; Accepted: January 16, 2018; Published online: August 20, 2018.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Sleep insufficiency has been reported with many types of musculoskeletal pain. The present study was designed to determine the relationship between sleep duration and osteoarthritis.
Methods: This study is based on data from 2013–2015 from the Sixth Korea National Health and Nutrition Examination Survey. The total number of participants who were adults over the age of 30 years was 13,316. The association between sleep duration and osteoarthritis was analyzed using multiple logistic regression. All results were adjusted for sex, age, obesity, smoking, alcohol, depression, and occupation to clarify the effect of sleep insufficiency on osteoarthritis.
Results: There was a statistically significant correlation between sleep duration and osteoarthritis; shorter sleep duration was associated with a greater risk of having osteoarthritis (odds ratio=1.217, P<0.05). The group with sleep duration longer than 8 hours did not have a significant difference in risk than the group of six to eight hours of sleep time. As to the effect of adjusted variables on osteoarthritis, women had a higher probability of having osteoarthritis than men. The physical labor group had a higher probability of having osteoarthritis than the non-physical labor group. The presence of depression was associated with a statistically significant probability of having osteoarthritis. Smoking and heavy alcohol consumption had no significant correlation with osteoarthritis.
Conclusion: This study demonstrates that there are statistically significant associations between sleep deficiency and osteoarthritis. Patients with osteoarthritis require active interventions to relieve sleep disorder.
Keywords: Sleep Duration; Korea National Health and Nutrition Exmination Survey; Musculoskeletal Pain; Osteoarthritis
References
  1. Pereira D, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E. The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review. Osteoarthritis Cartilage 2011; 19: 1270-85.
    Pubmed CrossRef
  2. Korea centers for disease control and prevention. The sixth Korea national health and nutrition exmination survey (KNHANESVI-3) [Internet]. Cheongju: KCDC [cited 2017 Jun 22].
    Available from: https://knhanes.cdc.go.kr/knhanes/sub04/sub04_03.do?classType=7
  3. Moldofsky H. Sleep and pain. Sleep Med Rev 2001; 5: 385-96.
    Pubmed CrossRef
  4. Smith MT, Haythornthwaite JA. How do sleep disturbance and chronic pain inter-relate? Insights from the longitudinal and cognitive-behavioral clinical trials literature. Sleep Med Rev 2004; 8: 119-32.
    CrossRef
  5. Arden N, Nevitt MC. Osteoarthritis: epidemiology. Best Pract Res Clin Rheumatol 2006; 20: 3-25.
    Pubmed CrossRef
  6. Malfait AM, Schnitzer TJ. Towards a mechanism-based approach to pain management in osteoarthritis. Nat Rev Rheumatol 2013; 9: 654-64.
    Pubmed KoreaMed CrossRef
  7. Call-Schmidt TA, Richardson SJ. Prevalence of sleep disturbance and its relationship to pain in adults with chronic pain. Pain Manag Nurs 2003; 4:124-33.
    CrossRef
  8. Alsaadi SM, McAuley JH, Hush JM, Bartlett DJ, Henschke N, Grunstein RR, et al. Detecting insomnia in patients with low back pain: accuracy of four self-report sleep measures. BMC Musculoskelet Disord 2013; 14: 196.
    Pubmed KoreaMed CrossRef
  9. Vgontzas AN, Zoumakis M, Papanicolaou DA, Bixler EO, Prolo P, Lin HM, et al. Chronic insomnia is associated with a shift of interleukin-6 and tumor necrosis factor secretion from nighttime to daytime. Metabolism 2002; 51:887-92.
    Pubmed CrossRef
  10. Livshits G, Zhai G, Hart DJ, Kato BS, Wang H, Williams FM, et al. Interleukin6 is a significant predictor of radiographic knee osteoarthritis: The chingford study. Arthritis Rheum 2009; 60: 2037-45.
    Pubmed KoreaMed CrossRef
  11. Vgontzas AN, Zoumakis M, Bixler EO, Lin HM, Prolo P, Vela-Bueno A, et al. Impaired nighttime sleep in healthy old versus young adults is associated with elevated plasma interleukin-6 and cortisol levels: physiologic and therapeutic implications. J Clin Endocrinol Metab 2003; 88: 2087-95.
    Pubmed CrossRef
  12. Haack M, Lee E, Cohen DA, Mullington JM. Activation of the prostaglandin system in response to sleep loss in healthy humans: potential mediator of increased spontaneous pain. Pain 2009; 145: 136-41.
    Pubmed KoreaMed CrossRef
  13. Lautenbacher S, Kundermann B, Krieg JC. Sleep deprivation and pain perception. Sleep Med Rev 2006; 10: 357-69.
    Pubmed CrossRef
  14. Leigh TJ, Hindmarch I, Bird HA, Wright V. Comparison of sleep in osteoarthritic patients and age and sex matched healthy controls. Ann Rheum Dis 1988; 47: 40-2.
    Pubmed KoreaMed CrossRef
  15. Campbell CM, Buenaver LF, Finan P, Bounds SC, Redding M, McCauley L, et al. Sleep, pain catastrophizing, and central sensitization in knee osteoarthritis patients with and without insomnia. Arthritis Care Res (Hoboken) 2015; 67: 1387-96.
    Pubmed KoreaMed CrossRef
  16. Allen KD, Renner JB, Devellis B, Helmick CG, Jordan JM. Osteoarthritis and sleep: the Johnston county osteoarthritis project. J Rheumatol 2008; 35:1102-7.
    Pubmed KoreaMed
  17. Finan PH, Goodin BR, Smith MT. The association of sleep and pain: an update and a path forward. J Pain 2013; 14: 1539-52.
    Pubmed KoreaMed CrossRef
  18. Campbell P, Tang N, McBeth J, Lewis M, Main CJ, Croft PR, et al. The role of sleep problems in the development of depression in those with persistent pain: a prospective cohort study. Sleep 2013; 36: 1693-8.
    Pubmed KoreaMed CrossRef
  19. Parmelee PA, Tighe CA, Dautovich ND. Sleep disturbance in osteoarthritis:linkages with pain, disability, and depressive symptoms. Arthritis Care Res (Hoboken) 2015; 67: 358-65.
    Pubmed KoreaMed CrossRef
  20. Prieto-Alhambra D, Judge A, Javaid MK, Cooper C, Diez-Perez A, Arden NK. Incidence and risk factors for clinically diagnosed knee, hip and hand osteoarthritis: influences of age, gender and osteoarthritis affecting other joints. Ann Rheum Dis 2014; 73: 1659-64.
    Pubmed KoreaMed CrossRef
  21. Smith MT, Quartana PJ, Okonkwo RM, Nasir A. Mechanisms by which sleep disturbance contributes to osteoarthritis pain: a conceptual model. Curr Pain Headache Rep 2009; 13: 447-54.
    Pubmed CrossRef
  22. Menefee LA, Cohen MJ, Anderson WR, Doghramji K, Frank ED, Lee H. Sleep disturbance and nonmalignant chronic pain: a comprehensive review of the literature. Pain Med 2000; 1: 156-72.
    Pubmed CrossRef
  23. Littner M, Kushida CA, Anderson WM, Bailey D, Berry RB, Davila DG, et al. Practice parameters for the role of actigraphy in the study of sleep and circadian rhythms: an update for 2002. Sleep 2003; 26: 337-41.
    Pubmed CrossRef

This Article


Services
Social Network Service

e-submission

Archives