Korean J Fam Pract 2019; 9(6): 506-512  https://doi.org/10.21215/kjfp.2019.9.6.506
The Status and Effects of Influenza and Pneumococcal Vaccination in Hospitalized Patients Population with Chronic Conditions
Oh Young Kim, Keun Mi Lee, Seung Pil Jung*
Department of Family Medicine, Yeungnam University Medical Center, Daegu, Korea
Seung Pil Jung
Tel: +82-53-620-3540, Fax: +82-53-654-2413
E-mail: spjung@yu.ac.kr
ORCID: http://orcid.org/0000-0002-1215-3624
Received: June 13, 2019; Revised: September 20, 2019; Accepted: September 25, 2019; Published online: December 20, 2019.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: This study was aimed to analyze the status and effects of influenza vaccine (IV) and pneumococcal vaccine (PV) in hospitalized patients in a University Hospital with chronic conditions.
Methods: The study is based on the medical records of 3,279 inpatients in pulmonary center of Yeungnam University Medical Center (Korea) between October 2015 and September 2016. The subjects were divided into two groups by age (under 65 years old and over 65 years old), and the preventive effects of IV and PV were analyzed by comparing vaccination rate, hospitalized period, pneumonia attach rate, and mortality rate. Vaccination data were obtained from the Korea Centers for Disease Control and Prevention web system. The chi-squared test, linear regression analysis and logistic regression analysis were used to analyze factors associated with the types of vaccinations and underlying medial factors.
Results: In the group under 65 years old, those without any vaccination had higher mortality rate. In addition, patients with IV vaccination were more likely to have shorter hospitalized periods. On the contrary, a group of people without any vaccination, hospitalized period increased. However, in the group of over 65 years old with various underlying conditions, the mortality rate was higher when IV or both IV and PV were vaccinated.
Conclusion: The preventive effects show the opposite results in two age groups. This study indicates that the vaccines are more effective in the group under 65 years old than the group over 65 years old with chronic conditions.
Keywords: Influenza Vaccines; Pneumococcal Vaccines; Mortality; Pneumonia; Hospitalization
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