Mean cortical thickness for clusters where a significant cortical atrophy was observed in obese patients compared to controls (FDR corrected, P<0.05)
| Region | Cortical thickness (mm) | No. of vertexes in cluster | Cluster size |
Talairach coordinates |
|||
|---|---|---|---|---|---|---|---|
| Obese group (n=10) | Control group (n=11) | ||||||
| Left | |||||||
| Supramarginal | 2.674±0.199 | 2.837±0.164 | 377 | 180.97 | -50.8 | -52.8 | 20.2 |
| Inferior parietal | 2.751±0.496 | 3.105±0.164 | 128 | 78.73 | -44.5 | -70.5 | 23 |
| Pars orbitalis | 2.697±0.270 | 3.135±0.280 | 90 | 42.21 | -44.2 | 40.2 | -13.4 |
| Pars opercularis | 2.600±0.263 | 2.793±0.155 | 14 | 5.72 | -42.2 | 13.1 | 4.9 |
Values are mean±standard deviation.
FDR, false discovery rate.
Statistical significance was tested using analysis of covariance adjusted for age, education, total intracranial volume, and gender.