Association between serum folic acid quartile and cardiovascular disease risk within 10 years
| Folic acid (ng/mL) | Quartile | OR (95% CI) |
P for trend |
|---|---|---|---|
| Total | |||
| Q1 (<5.2) | 854 (27.5) | 5.08 (3.56–7.20) | <0.001 |
| Q2 (5.2–7.2) | 792 (24.7) | 2.19 (1.53–3.14) | |
| Q3 (7.2–10.1) | 819 (24.9) | 1.41 (0.99–2.00) | |
| Q4 (>10.1) | 817 (22.9) | 1.00 (ref) | |
| Male | |||
| Q1 (<4.4) | 358 (27.4) | 2.27 (1.37–3.77) | 0.01 |
| Q2 (4.4–5.9) | 313 (23.7) | 1.48 (0.86–2.53) | |
| Q3 (5.9–8.4) | 326 (26.0) | 1.30 (0.79–2.14) | |
| Q4 (>8.4) | 321 (22.9) | 1.00 (ref) | |
| Female | |||
| Q1 (<6.0) | 508 (26.5) | 2.06 (1.05–4.06) | 0.03 |
| Q2 (6.0–8.2) | 483 (25.0) | 0.99 (0.52–1.89) | |
| Q3 (8.2–11.0) | 479 (23.6) | 0.71 (0.37–1.37) | |
| Q4 (>11.0) | 494 (24.9) | 1.00 (ref) |
Values are presented as number (%).
OR, odds ratio; CI, confidence interval.
aBy logistic regression adjusted for age, body mass index, household income, and alcohol intake.