Laboratory findings of patients infected with COVID-19 on admission
| Variable | National Institutes of Health clinical spectrum | P-value | |||
|---|---|---|---|---|---|
| Total (n=214) |
Asymptomatic/mild illness (n=104) |
Moderate illness (n=63) |
Severe/critical illness (n=47) |
||
| White-cell count (×103/μL) | 5.42±2.03 | 5.57±1.90 | 5.14±1.95 | 5.46±2.38 | 0.409 |
| Neutrophil count (×103/μL) | 3.35±1.74 | 3.28±1.60 | 3.09±1.51 | 3.86±2.21 | 0.132 |
| Lymphocyte count (×103/μL) | 1.53±0.58 | 1.75±0.55 | 1.48±0.55 | 1.14±0.47 | <0.001 |
| Lymphocytopenia |
108 (50.5) | 34 (32.7) | 38 (60.3) | 36 (76.6) | <0.001 |
| Hemoglobin (g/dL) | 13.10±1.64 | 13.26±1.58 | 13.18±1.59 | 12.61±1.77 | 0.073 |
| Platelet count (103/μL) | 213.8±67.8 | 229.5±66.7 | 208.5±68.1 | 186.3±60.9 | 0.001 |
| Total protein (g/dL) | 7.16±0.54 | 7.29±0.52 | 7.13±0.48 | 6.91±0.59 | <0.001 |
| Albumin (g/dL) | 4.14±0.29 | 4.21±0.29 | 4.13±0.27 | 3.98±0.31 | <0.001 |
| Total bilirubin (mg/dL) | 0.52±0.24 | 0.55±0.28 | 0.48±0.16 | 0.52±0.24 | 0.177 |
| AST (IU/L) | 31.2±22.2 | 26.0±11.5 | 29.8±12.8 | 44.4±39.1 | 0.003 |
| ALT (IU/L) | 28.5±31.8 | 25.4±24.5 | 26.8±18.6 | 38.0±52.5 | 0.297 |
| BUN (mg/dL) | 12.18±5.55 | 11.99±3.71 | 11.27±3.94 | 13.81±9.34 | 0.174 |
| Creatinine (mg/dL) | 0.81±0.27 | 0.80±0.17 | 0.76±0.15 | 0.91±0.48 | 0.093 |
| LDH (IU/L) | 463.9±199.1 | 400.7±151.4 | 488.2±220.9 | 571.0±212.0 | <0.001 |
| C-reactive protein (mg/dL) | 1.438±2.916 | 0.332±0.880 | 1.393±2.542 | 3.945±4.444 | <0.001 |
Values are presented as mean±standard deviation or number (%).
COVID-19, coronavirus disease 2019; AST, aspartate aminotransferase; ALT, alanine aminotransferase; BUN, blood urea nitrogen; LDH, lactate dehydrogenase.
aLymphocytopenia is defined as a lymphocyte count of less than 1,500 cells per cubic millimeter. bP-value by chi-square test.
P-value was calculated by ANOVA.