Korean Journal of Family Practice

Table. 3.

Logistic regression analysis of the relation between variables and elevated ALT

Variables Crude ORa (95% CI) P-valuea Adjusted ORb (95% CI) P-valueb
BMI
Obesity 19.86 (8.86–44.50) <0.001 15.41 (7.28–32.59) <0.001
Overweight 5.15 (1.88–14.10) 0.001 4.02 (1.44–11.23) 0.008
Normal 1 1
HTN
Yes 2.97 (1.59–5.58) 0.001 1.33 (0.65–2.73) 0.432
No 1 1
Fasting glucose
DM 36.29 (4.88–269.77) <0.001 20.88 (3.23–134.86) 0.001
IFG 3.19 (1.52–6.71) 0.002 2.95 (1.20–7.27) 0.019
Total cholesterol
High 2.00 (0.91–4.36) 0.083 1.76 (0.62–4.97) 0.285
Normal 1 1
Triglyceride
High 3.40 (1.67–6.92) 0.001 1.10 (0.47–2.61) 0.825
Normal 1 1
HDL-C
Low 7.83 (4.11–14.91) <0.001 1.55 (0.79–3.06) 0.203
Normal 1 1
LDL-C
High 1.80 (0.82–3.99) 0.134 0.69 (0.21–2.27) 0.542
Normal 1 1
Smoking
Yes 2.45 (0.92–6.51) 0.073 1.84 (0.56–6.08) 0.316
No 1 1
Alcohol
Yes 0.90 (0.47–1.75) 0.760 0.56 (0.24–1.30) 0.175
No 1 1
Muscular exercise
Yes 1.06 (0.54–2.08) 0.868 1.16 (0.55–2.45) 0.692
No 1 1
Family history of HTN, DM, DL
Yes 2.87 (1.59–5.20) 0.001 2.03 (0.99–4.15) 0.052
No 1 1

ALT, alanine aminotransferase; OR, odds ratio; CI, confidence interval; BMI, body mass index; HTN, hypertension; DM, diabetes mellitus; IFG, impaired fasting glucose; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; DL, dyslipidemia.

aCrude odds ratio by logistic regression. bAdjusted for age, sex, BMI, HTN, fasting glucose, high total cholesterol, high triglyceride, low HDL-C, high LDL-C, smoking, alcohol, muscular exercise, family history of HTN, DM, DL.

Korean J Fam Pract 2022;12:86~92 https://doi.org/10.21215/kjfp.2022.12.2.86
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