Pneumococcal vaccine schedules for adults by underlying conditions
| Conditions | PCV15 |
PPSV23 → PCV15 |
Additional PPSV23 vaccination | Maximum number of additional PPSV vaccination |
|---|---|---|---|---|
| ≥65 years of age | ≥1 year after PCV15 dose | ≥1 year after PPSV23 dose | No further vaccination | 1 time |
| Chronic conditions |
≥1 year after PCV15 dose | ≥1 year after PPSV23 dose | ≥65 years of age & ≥5 years after PPSV23 | 2 times (1 time ≥65 years of age) |
| Increased risk for meningitis (e.g., CSF leak, cochlear implant) | ≥8 weeks after PCV15 dose | ≥1 year after PPSV23 dose | ≥65 years of age & ≥5 years after PPSV23 | 2 times (1 time ≥65 years of age) |
| Immunocompromised patients, asplenia | ≥8 weeks after PCV15 dose | ≥1 year after PPSV23 dose | 5 years after first PPSV23 dose, ≥65 years of age & ≥5 years after second PPSV23 dose |
3 times (1 time ≥65 years of age) |
PCV15, 15-valent pneumococcal conjugate vaccine; PPSV23, 23-valent pneumococcal polysaccharide vaccine; PPSV, pneumococcal polysaccharide vaccine; CSF, cerebrospinal fluid.
aIf PCV15 cannot be administered, PCV13 can be administered.
bChronic conditions include alcohol abuse disorder, chronic heart disease, chronic liver disease, chronic lung disease, cigarette smoking, and diabetes mellitus.