Korean J Fam Pract. 2016; 6(1): 8-13  https://doi.org/10.21215/kjfp.2016.6.1.8
Relationship between Exercise and Gamma-Glutamyltransferase in Korean
Hyo-Jae Son1, Soo-Young Kim1,*, Sunyoung Chun2, Ji-Soo Seo1
1Department of Family Medicine, Kangdong Sacred Heart Hospital, Seoul; 2Department of Family Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea
Soo-Young Kim
Tel: +82-2-2224-2406, Fax: +82-2-473-7387
E-mail: pclove@hallym.or.kr
Received: February 27, 2015; Revised: February 27, 2015; Accepted: August 20, 2015; Published online: February 20, 2016.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: The present study investigated the association between physical activity and serum gamma-glutamyltransferase (GGT) levels, a factor influencing cardiovascular disease. Serum GGT levels are associated with oxidative stress, and oxidative stress is associated with physical activity intensity and duration. We studied the relationship between exercise and GGT levels in Korean adults.
Methods: Data from the fifth Korean National Health and Nutrition Examination Survey (2010?2011) were used to analyze 10,159 women and men. Subjects were divided into four groups based on the quartile of GGT. Multiple logistic regression analysis was performed after adjusting for age, sex, body mass index, alcohol drinking, income, education, occupation, living alone and presence of diabetes mellitus, hypertension, or dyslipidemia in order to determine the association between physical activity and serum GGT levels.
Results: Walking was significantly associated with serum GGT levels in men. We found a significant association between walking time per week and low GGT levels in men (P for trend ≤0.0001). However, there was no statistically significant relationship between other exercise types and GGT levels, nor was there a statistically significant relationship between exercise type and GGT levels in women. After adjusting for confounders, the odds ratio (95% confidence interval) for serum GGT levels compared with the non-walking group in men was 1.334 (1.076?1.652).
Conclusion: Walking is significantly associated with serum GGT levels in Korean men.
Keywords: Physical Activity; gamma-Glutamyltransferase; Cardiovascular Diseases
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