Korean J Fam Pract. 2016; 6(4): 288-292  https://doi.org/10.21215/kjfp.2016.6.4.288
The Comparison of the Blood Level of 25-Hydroxyvitamin D3 in Healthy Adult and Patients with Herpes Zoster
Gyeong-Yoon Han, Young-Ah Choi*, Kyung-Shik Lee, Young-Kyu Park, Sung-Min Cho, Minji Shim, Byungkook Kim, So-Youn Kim
Department of Family Medicine, Bundang Jesaeng Hospital, Seongnam, Korea
Young-Ah Choi
Tel: +82-31-779-0152, Fax: +82-31-779-0169, E-mail: grchoi1@dmc.or.kr
Received: March 14, 2016; Revised: April 27, 2016; Accepted: May 5, 2016; Published online: August 20, 2016.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract

Background: This study compared serum levels of 25-hydroxyvitamin D3 in healthy adults with those in patients with herpes zoster.

Methods: A total of 1,483 subjects were selected among adults (aged ≥50 years) who had visited a health promotion center from October 1, 2014, to July 15, 2015. During the same period, a total of 30 subjects were selected among adults (aged ≥50 years) who were hospitalized for herpes zoster. 25-hydroxyvitamin D3 was measured using a chemiluminescence immunoassay.

Results: Multiple factors can influence herpes zoster incidence, such as sex, smoking, drinking, season, age, and height. After adjusting for these factors by logistic regression analysis, we found that the effect of serum levels of 25-hydroxyvitamin D3 on herpes zoster was statistically different between the two groups (odds ratio, 0.901; 95% confidence interval, 0.838?0.969).

Conclusion: The differences in the serum levels of 25-hydroxyvitamin D3 between the two groups were statistically significant. As 25-hydroxyvitamin D3 increased, the incidence of herpes zoster decreased.

Keywords: Herpes Zoster; The Serum Level of 25-Hydroxyvitamin D3; Chemiluminescence Immunoassay
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