Korean J Fam Pract 2020; 10(6): 469-473  https://doi.org/10.21215/kjfp.2020.10.6.469
Association between Sitting Time and Hyperuricemia in Korean Adults: Results from the 2016–2018 Korea National Health and Nutrition Examination Survey
Joo Yeon Kim1, Ga Eun Nam1,*, Youn Huh2, Yu Sun Her1, Chan Mi Park1, Wonsock Kim1, Yang-Hyun Kim1, Kyung-Hwan Cho1
1Department of Family Medicine, Korea University Anam Hospital, Korea University College of Medicine; 2Department of Family Medicine, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea
Ga Eun Nam
Tel: +82-2-920-5104, Fax: +82-2-928-8083
E-mail: namgaaa@daum.net
ORCID: https://orcid.org/0000-0002-6739-9904
Received: August 13, 2020; Revised: November 8, 2020; Accepted: November 15, 2020; Published online: December 20, 2020.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Recent studies have indicated that hyperuricemia is associated with metabolic syndrome and cardiovascular diseases. We aimed to examine the association between sitting time and hyperuricemia in Korean adults.
Methods: This study included 16,535 adults aged ≥19 years who participated in the 2016–2018 Korea National Health and Nutrition Examination Survey. Hyperuricemia was defined as a serum uric acid level of ≥7.0 mg/dL in men and ≥6.0 mg/dL in women. The odds ratios and 95% confidence intervals of hyperuricemia according to sitting time were calculated using a multivariable logistic regression analysis.
Results: The mean serum uric acid levels were significantly higher in participants with sitting times of ≥5 hours/day than those with sitting times of <5 hours/day in total participants, males, and females. The proportion of hyperuricemia was also significantly higher in participants with sitting times of ≥5 hours/day than those with sitting times of <5 hours/day in the total participants and males. Before and after adjusting for confounding variables, sitting times of ≥5 hours/day were associated with increased odds of hyperuricemia as compared with sitting times of <5 hours/day in total participants.
Conclusion: Our findings suggest that longer sitting time is associated with risk of hyperuricemia, and sitting time is an independent factor for hyperuricemia in Korean adults.
Keywords: Uric Acid; Hyperuricemia; Sitting Time; Korea National Health and Nutrition Examination Survey
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