Korean J Fam Pract. 2018; 8(5): 684-689  https://doi.org/10.21215/kjfp.2018.8.5.684
The Relation of High-Sensitivity C-Reactive Protein with Metabolic Syndrome in Korean Adults: Based on the Korean Health and Nutrition Examination Survey, 2015
Sung Kyum Kim, Jin A Park*, Sang Keun Ham, Min Woo Shin, Eun Hye Yu, Yong Ho Sohn
Department of Family Medicine, Hanil General Hospital, Seoul, Korea
Jin A Park
Tel: +82-2-901-3114, Fax: +82-2-901-3174
E-mail: 03680528@hanilmed.net
ORCID: http://orcid.org/0000-0001-6982-9309
Received: July 21, 2017; Revised: October 24, 2017; Accepted: October 26, 2017; Published online: October 20, 2018.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Metabolic syndrome is a group of multiple metabolic disorders that increase the risk of cardiovascular diseases and type 2 diabetes. C-reactive protein (CRP) level is a marker of systemic inflammation, and its correlation with coronary arterial disease has recently been highlighted. The purpose of this study was to determine the relationship between metabolic syndrome and CRP level, as well as between each metabolic syndrome component and CRP level.
Methods: On the basis of the data from the Sixth Korea National Health and Nutrition Examination Survey conducted in 2015, 3,705 people were selected. They were grouped according to general and lifestyle characteristics such as age, sex, alcohol drinking, and smoking status. The correlation of high-sensitivity (hs-CRP) level according to these variables was analyzed statistically. The correlation between each component of the metabolic syndrome and hs-CRP level was examined using one-way analysis of variance. Finally, the association of hs-CRP level with metabolic syndrome was examined using logistic regression analysis.
Results: hs-CRP level correlated with male sex, age, high-risk drinking, and smoking status. Overall, high hs-CRP level correlated with the high incidence rate of metabolic syndrome. The metabolic syndrome components such as waist circumference, triglyceride level, high-density lipoprotein cholesterol level, blood pressure, and blood glucose level showed statistically significant correlations with hs-CRP level.
Conclusion: Each metabolic syndrome component showed a significant difference according to hs-CRP level. The group with metabolic syndrome had a high hs-CRP level as a whole. This study showed that high hs-CRP levels were also associated with the prevalence of metabolic syndrome.
Keywords: Korea National Health and Nutrition Examination Survey; Metabolic Syndrome; High-Sensitivity C-Reactive Protein; Korean Adult
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