Korean J Fam Pract 2019; 9(5): 454-459  https://doi.org/10.21215/kjfp.2019.9.5.454
Influence of Fine Particulate Dust Particulate Matter 10 on Respiratory Virus Infection in the Republic of Korea
Ji Min Cheon, Yun Jun Yang*, Yeong Sook Yoon, Eon Sook Lee, Jun Hyung Lee, Youn Huh, Jung Won Mun, Chang Hyun Jhung, Bo Ra Hyun
Department of Family Medicine, Inje University Ilsan-Paik Hospital, Goyang, Korea
Yun Jun Yang
Tel: +82-31-910-7114, Fax: +82-31-910-7518
E-mail: jyang@paik.ac.kr
ORCID: http://orcid.org/0000-0003-3428-1587
Received: October 11, 2018; Revised: August 25, 2019; Accepted: August 31, 2019; Published online: October 20, 2019.
© The Korean Academy of Family Medicine. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: This study investigated the effect of fine dust concentrations in the air on the incidence of viral respiratory infections in the Republic of Korea.
Methods: A time series analysis using R statistics was performed to determine the relationship between weekly concentrations of fine dust in the air and the incidences of acute respiratory tract infections caused by the respiratory syncytial virus (RSV), adenovirus (HAdV), rhinovirus (HRV), human metapneumovirus (HMPV), human coronavirus (HCoV), human bocavirus (HBoV), human parainfluenza virus (HPIV), and influenza virus (IFV), from the beginning of 2016 to the end of 2017. Correlations between various meteorological factors and the amount of fine dust were analyzed using the Spearman's rank correlation coefficient. To analyze the relationship between viral infections and fine dust, a quasi-poisson analysis was performed.
Results: The incidence of the HAdV was proportional to fine dust and air temperature. The IFV was proportional to fine dust and relative humidity and was inversely proportional to temperature. The HMPV was proportional to fine dust, wind speed, and inversely proportional to relative humidity. The HCoV was proportional to micro dust, relative humidity, and inversely proportional to temperature. Both the HBoV and HPIV were directly proportional to fine dust, temperature, wind speed, and inversely proportional to relative humidity. The RSV was inversely proportional to fine dust, temperature, wind speed. A lag effect was observed for the influenza virus, in that its incidence increased 2-3 weeks later on the cumulative lag model.
Conclusion: As the weekly average concentration of fine dust increases, the incidence of HAdV, HMPV, HCoV, HBoV, HPIV, and influenza increase.
Keywords: Air Pollution; Meteorological Factors; Viruses; Respiration Disorder
References
  1. Kwon HJ. Toxicity and health effects of Asian dust: a literature review. J Korean Med Assoc 2012; 55: 234-42.
    CrossRef
  2. Jeon W, Kim H. Associations of air pollution on asthma hospitalization in Seoul and Shanghai. Korean J Public Health 2016; 53: 17-26.
    CrossRef
  3. Park JW. Effects of asian dust events on peak expiratory flow rate and respiratory symptoms in asthmatic patients and viral transport [dissertation]. Incheon: Inha Univ.; 2004. Korean.
  4. Oh JS, Park SH, Kwak MK, Pyo CH, Park KH, Kim HB, et al. Ambient particulate matter and emergency department visit for chronic obstructive pulmonary disease. J Korean Soc Emerg Med 2017; 28: 32-9.
  5. Chen G, Zhang W, Li S, Zhang Y, Williams G, Huxley R, et al. The impact of ambient fine particles on influenza transmission and the modification effects of temperature in China: a multi-city study. Environ Int 2017; 98: 82-8.
    Pubmed CrossRef
  6. Ciencewicki J, Jaspers I. Air pollution and respiratory viral infection. Inhal Toxicol 2007; 19: 1135-46.
    Pubmed CrossRef
  7. Shin DC. Health effects of ambient particulate matter. J Korean Med Assoc 2007; 50: 175-82.
    CrossRef
  8. Liu Y, Guo Y, Wang C, Li W, Lu J, Shen S, et al. Association between temperature change and outpatient visits for respiratory tract infections among children in Guangzhou, China. Int J Environ Res Public Health 2015; 12: 439-54.
    Pubmed KoreaMed CrossRef
  9. Kim KY, Kim YS, Lee CM, Cho MS, Byeon SH. Atmospheric distribution characteristics of airborne bacteria in part of Seoul area. J KOSAE 2009; 25: 493-502.
    CrossRef
  10. Lee S, Choi B, Yi SM, Ko G. Characterization of microbial community during Asian dust events in Korea. Sci Total Environ 2009; 407: 5308-14.
    Pubmed CrossRef
  11. Park JW, Lim YH, Kyung SY, An CH, Lee SP, Jeong SH. Detection of pathogenic viruses in the atmosphere during Asian dust events in Incheon city. Tuberc Respir Dis 2005; 59: 279-85.
    CrossRef
  12. Imai C, Hashizume M. A systematic review of methodology: time series regression analysis for environmental factors and infectious diseases. Trop Med Health 2015; 43: 1-9.
    Pubmed KoreaMed CrossRef
  13. Vandini S, Corvaglia L, Alessandroni R, Aquilano G, Marsico C, Spinelli M, et al. Respiratory syncytial virus infection in infants and correlation with meteorological factors and air pollutants. Ital J Pediatr 2013; 39: 1.
    Pubmed KoreaMed CrossRef
  14. Liu Y, Xie S, Yu Q, Huo X, Ming X, Wang J, et al. Short-term effects of ambient air pollution on pediatric outpatient visits for respiratory diseases in Yichang city, China. Environ Pollut 2017; 227: 116-24.
    Pubmed CrossRef
  15. Zhu L, Ge X, Chen Y, Zeng X, Pan W, Zhang X, et al. Short-term effects of ambient air pollution and childhood lower respiratory diseases. Sci Rep 2017; 7: 4414.
    Pubmed KoreaMed CrossRef
  16. Cao C, Jiang W, Wang B, Fang J, Lang J, Tian G, et al. Inhalable microorganisms in Beijing’s PM2.5 and PM10 pollutants during a severe smog event. Environ Sci Technol 2014; 48: 1499-507.
    Pubmed KoreaMed CrossRef
  17. Jusot JF, Adamou L, Collard JM. Influenza transmission during a one-year period (2009-2010) in a Sahelian city: low temperature plays a major role. Influenza Other Respir Viruses 2012; 6: 87-9.
    Pubmed KoreaMed CrossRef
  18. Imai C, Armstrong B, Chalabi Z, Mangtani P, Hashizume M. Time series regression model for infectious disease and weather. Environ Res 2015; 142: 319-27.
    Pubmed CrossRef
  19. Pica N, Bouvier NM. Environmental factors affecting the transmission of respiratory viruses. Curr Opin Virol 2012; 2: 90-5.
    Pubmed KoreaMed CrossRef
  20. Nenna R, Evangelisti M, Frassanito A, Scagnolari C, Pierangeli A, Antonelli G, et al. Respiratory syncytial virus bronchiolitis, weather conditions and air pollution in an Italian urban area: an observational study. Environ Res 2017; 158: 188-93.
    Pubmed CrossRef
  21. Hu W, Williams G, Phung H, Birrell F, Tong S, Mengersen K, et al. Did socioecological factors drive the spatiotemporal patterns of pandemic influenza A (H1N1)? Environ Int 2012; 45: 39-43.
    Pubmed CrossRef
  22. Bhatt JM, Everard ML. Do environmental pollutants influence the onset of respiratory syncytial virus epidemics or disease severity? Paediatr Respir Rev 2004; 5: 333-8.
    Pubmed CrossRef
  23. Yeo NK, Hwang YJ, Kim ST, Kwon HJ, Jang YJ. Asian sand dust enhances rhinovirus-induced cytokine secretion and viral replication in human nasal epithelial cells. Inhal Toxicol 2010; 22: 1038-45.
    Pubmed CrossRef
  24. Lessler J, Brookmeyer R, Reich NG, Nelson KE, Cummings DA, Perl TM. Identifying the probable timing and setting of respiratory virus infections. Infect Control Hosp Epidemiol 2010; 31: 809-15.
    Pubmed CrossRef


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